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Blood Thinning vs. Blood Viscosity

Many people ask whether Neprinol is a blood thinner. The short answer is no—but it can support healthy blood viscosity, as it is comprised of protein-dissolving enzymes that support healthy circulation. To better understand the difference between blood thinning and blood viscosity, let’s first take a look at the blood clotting process.

When an injury leads to blood vessel damage, blood cells called platelets immediately begin to accumulate at the injury site to form a plug on the vessel wall [1]. Platelets also interact with a protein called fibrin that promotes the formation of a blood clot. Fibrin consists of strong fibers that encase blood cells, platelets, and blood plasma (liquid portion of blood) to create a clot that prevents excessive bleeding.

When healing of the blood vessel wall is almost complete, another protein called plasmin becomes activated. Plasmin helps dissolve the fibrin-based blood clot when it is no longer needed [1]. Under healthy states, the body regulates this process without complication. However, if too much clotting occurs, a clot may block a blood vessel and disrupt blood flow. Blood clots in certain parts of the body can become life-threatening and blood thinners may be recommended in such cases.

Blood thinners, which are also called anticoagulants, are typically administered when a blood clot develops in a large vein found in the leg or travels toward the heart or lungs [2]. This form of treatment stops blood clots from getting bigger and prevents new clots from forming, but does not dissolve blood clots [2].

There are different types of blood thinners on the market that prevent platelets from clumping to form a plug or block proteins from binding to platelets and cells. Blood thinners should be used with caution because they disrupt the normal blood clotting process and this can lead to serious or dangerous side effects (e.g., excessive bleeding, chest pain, nausea) [2]. Blood viscosity in simple terms, refers to how sticky the blood is, and how easily it can flow through the circulatory system. 

Neprinol – Gentle Blood Viscosity Support

Neprinol supports healthy blood viscosity with its powerful combination of fibrinolytic enzymes (fibrin digesting) [3-6]. Two of the key enzymes are serrapeptase and nattokinase, which target fibrin and other proteins [3, 5].

In response to clot formation, the body may also experience swelling and  inflammation as part of the natural healing process [1, 2]. Serrapeptase helps support healthy levels of fibrin  as well as proteins linked to the body's natural healing and repair mechanisms [3, 4]. This means regular serrapeptase supplementation:

  • Supports natural blood cleansing
  • Reinforces healthy circulation

Similarly, nattokinase is another fibrinolytic (fibrin-dissolving) enzyme that demonstrates the unmatched ability to support healthy fibrin levels [5-7].

Evidence also shows that nattokinase supplementation [7]:

  • Helps support healthy levels of fibrin
  • Supports healthy circulation by promoting blood cleansing

Together, the serrapeptase and nattokinase enzymes in Neprinol support healthy blood viscosity without altering the body’s natural blood clotting and degradation pathways. Most importantly, taking Neprinol does not block the clotting process in a way that would cause excessive bleeding. The science-based formula simply supports healthy blood viscosity to reinforce the body’s ability to safely and naturally recover during the clotting process. 


  1. Pieters M, Wolberg AS. Fibrinogen and fibrin: An illustrated review. Res Pract Thromb Haemost. 2019;3(2):161-172.
  2. Fox BD, Kahn SR, Langleben D, et al. Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials. BMJ. 2012;345:e7498-e7519.
  3. Mazzone A, Catalani M, Costanzo M, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: A multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990;18(5):379-388.
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  6. Sumi H, Hamada H, Tsushima H, et al. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese natto: A typical and popular soybean food in the Japanese diet. Experientia. 1987;43(10):1110-1111.
  7. Ren NN, Chen HJ, Li Y, Mcgowan GW, Lin YG. [A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia]. Zhonghua Yi Xue Za Zhi. 2017;97(26):2038-2042.
  8. Rajamäki K, Lappalainen J, OOrni K, et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation. PLoS One. 2010;5(7):e11765-e11790.
  9. Galkina E, Ley K. Immune and inflammatory mechanisms of atherosclerosis. Annu Rev Immunol. 2009;27:165-197.