Neprinol Supports Lung and Respiratory Health*
The respiratory system is made up of the nose, sinuses, mouth, throat, voice box, windpipe, lungs, diaphragm and blood vessels. The main function of this system is to bring in oxygen-rich air to power the body's cellular processes and to release carbon dioxide.
The average person breathes about 25,000 times during a normal day. For a healthy person this process is easy, but when the health of the respiratory system is compromised breathing is not so simple, particularly for those who suffer from allergies.
Allergies is the 6th leading cause of chronic health problems in the U.S., with more than 50 million Americans experiencing allergy-related issues such as sinus irritation, hay fever, food allergies, allergy-induced skin problems, and persistent breathing issues . The number of people who have hay fever or allergy-related breathing problems, in particular, has rapidly increased over the years . This increase is attributed to early blooming due to consistent climate changes (e.g., warmer seasonal temperatures and winters), exposing people to higher levels of pollen for longer periods [2, 3].
Ozone levels and ozone pollution (e.g., car emissions) can also influence respiratory health . Ozone is a gas that is comprised of three oxygen atoms. In the upper atmosphere, the ozone forms a protective layer that shields the earth’s surface from the sun’s ultraviolet rays. Conversely, ground-level ozone, which develops due to chemical reactions between volatile organic compounds and nitrogen oxide molecules, can be harmful when the ozone levels increase 
Ozone pollutants that are released by power plants, cars, refineries, chemical plants, and industrial boilers that react when exposed to sunlight are compounding this problem. Furthermore, issues such as throat and lung irritation, coughing, wheezing, trouble breathing, and chest pain while breathing are all associated with higher ozone levels that are linked to warmer temperatures . This is one of the reasons people are more likely to experience health issues during the summer months.
Another health risk is wildfire smoke, which is a mixture of gases and small particles that are released into the air from burning plants, trees, buildings, or other toxic materials. Although wildfire smoke can make anyone feel ill, people with allergies or breathing problems are more susceptible to issues, including: irritated sinuses, breathing attacks, shortness of breath, stinging eyes, irregular heartbeat, coughing, and headaches, among others .
Together, the combination of early blooming, high ozone levels, and wildfire smoke are harmful factors that can lead to poor air quality. Reduced air quality increases the risks for healthy people as well as those who have chronic health problems. Nutritional supplementation with natural products helps counteract unhealthy environmental conditions by supporting the health of the respiratory system.
Boost Lung Health Naturally with Neprinol
Neprinol, by Arthur Andrew Medical, is a revolutionary dietary supplement that contains a protease blend, botanical enzymes (e.g., amla, papain, bromelain, rutin), and a systemic enzyme blend (serrapeptase, nattokinase, lipase) that support healthy respiratory health [1-10].* The blend of enzymes in Neprinol is similar to digestive enzymes, but primarily target the bloodstream rather than the gastrointestinal tract. Once in the bloodstream, these enzymes have full access to all of the cells and tissues in the body.* Recent medical breakthroughs have led researchers to use the proteolytic (protein-dissolving), mucus-thinning, nasal decongesting, and immune system-strengthening properties of beneficial enzymes to support the health of the respiratory system [1-10].*
For individuals who prefer to take just serrapeptase, Serretia is a good choice. Serrapeptase is a highly potent natural mucus-thinning enzyme that also targets nasal congestion. More specifically, this powerful enzyme dissolves mucus and supports healthier responses to inflammation that help the body address sinus pressure and congestion naturally.
Allergens, ozone pollution, wildfire smoke, and poor air quality can lead to tissue irritation that initiates the body’s natural immune response. Immune cells signal the release of various particles that travel to the site of irritation to initiate a cascade of events that promote natural healing. However, extensive or uncontrolled irritation can lead to an overactive immune system response that can worsen respiratory health. This can also lead to allergy issues, breathing problems, or respiratory tissue damage.
Serrapeptase helps address these types of issues by making fluids that are associated with irritation (e.g., mucus) less viscous [11, 12]. This promotes rapid drainage away from the site of irritation, thereby supporting a stronger immune system response [11, 12]. Overall, serrapeptase is a potent, systemic enzyme that influences various processes that are linked to abnormal inflammatory and immune responses. By enhancing the body’s ability to target and excrete harmful particles (e.g., allergens, fine particles, pollutants), serrapeptase supplementation supports optimal respiratory health.
Individuals who are looking for more complete enzymatic support should consider taking Neprinol regularly as it contains a scientifically supported blend of enzymes and antioxidants the promote strong respiratory function.
Neprinol Supports Healthy Levels of Fibrin*
Fibrin is a protein formed in the human body that can significantly impact health and general wellbeing – for better and for worse. Since scar tissue and clotting are comprised mainly of fibrin, this protein plays a vital role in the healing process. However, a number of different conditions are associated with the buildup of scar tissue in the lungs [13-15].
Microscopic damage to the alveoli (air sacs) and interstitial tissues (tissue between cells) of the lungs causes inflammation and scar tissue to develop. As this scar tissue builds up in the lungs it eventually causes the usually soft, permeable tissue to become stiff and thick, which makes breathing extremely difficult. This buildup of fibrin is thought to be linked to excessive amounts of plasminogen activator inhibitor-1 (PAI-1) .* PAI-1 prevents the conversion of the protein plasminogen into plasmin, a blood enzyme that degrades many blood proteins, most notably fibrin. Without plasminogen being converted into plasmin, the body's ability to naturally dissolve fibrin is drastically reduced.
Research has shown that protein-dissolving enzymes like those found in Neprinol can slow the production of fibrin and enhance its removal [17-21].* In laboratory studies, researchers have found that nattokinase, an enzyme extracted from a Japanese fermented soybean food called natto, works in much the same way as plasmin , which means that nattokinase has the potential to literally dissolve fibrin .* In fact, nattokinase has been clinically shown in animal models to be four times more potent than plasmin itself .* Nattokinase also blocks the activity of PAI-1, which boosts its fibrin-degrading capacity even more [23,24].*
Bromelain is a pineapple extract that contains a number of fibrin-degrading enzymes [25,26], as well as enzymes that enhance this fibrin-dissolving action .* Bromelain has also been shown to increase the conversion of plasminogen into plasmin [27-29], as well as prevent the conversion of fibrinogen to fibrin .* Serrapeptase is a protein-degrading enzyme that was first isolated from the silk worm  that has demonstrated significant anti-inflammatory and fibrin-removal activity .* Fungal proteases also have well characterized fibrinolytic properties, as demonstrated by their ability to breakdown fibrin and fibrinogen [32,33].*
Neprinol Supports Normal Levels of Inflammation*
Inflammation has also been shown to negatively affect respiratory function [34-36]. Researchers have found that systemic enzymes like those found in Neprinol can help support a normal inflammatory response [5,25,26,37,38].* Of these enzymes, bromelain has been shown to have the most potent effects within the respiratory system [6-10].*
In laboratory studies, bromelain has been shown to block some of the chemicals that promote and accelerate the process of inflammation [25,39,40].* Research has also shown that bromelain is especially effective at decreasing the migration of neutrophils, a type of white blood cell, to inflamed areas.* One in vitro study measured a 50-85% decrease in neutrophil migration with the use of bromelain .* This is especially important for respiratory health as neutrophils are thought to be a major contributor to declining lung health and function . That is because once neutrophils reach the site of inflammation, they produce a number of chemical substances that promote both lung injury and scar tissue formation . Bromelain has also been shown to support healthy levels of inflammation in other parts of the respiratory system, mainly within the sinuses [6-10].*
Neprinol Supports Normal Mucus Production and Clearance*
Mucus is an important substance produced within the respiratory system. In the upper respiratory tract it is produced to trap incoming pathogens (disease causing agents) so they can be destroyed and removed by the immune system. Mucus is also vital for the normal functioning of the lungs. However, sometimes mucus can be overproduced and become thick and difficult to expel, promoting infection and lung tissue damage, as well as contributing to declining respiratory function .
Serrapeptase has been shown in at least two clinical trials to support normal mucus thickness and healthy mucus clearance from the lungs [3,4].*
Are Neprinol and Serretia Safe?
No serious or adverse side effects have been reported from taking the ingredients in Neprinol or Serretia.* Clinical studies have shown that even extremely large doses of the systemic enzymes are not toxic. If you are taking blood-thinning medication or are pregnant or nursing, you should consult with your physician before taking Neprinol or Serretia.
* These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease. For all conditions or illnesses, see a healthcare professional for a full evaluation, diagnosis or treatment plan.
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