I have been on bio-identical hormones, estradiol patch, and estrogel to keep the hot flashes and other crazy menopausal symptoms away. However, after doing these for 10 years, I wanted to do natural remedies. The search had been so exhausting, and I almost went back to estrogel because menopausal symptoms were unbearable. Now, I have found my best friend!! Fibrovera has a made a HUGE difference!! It hasn't stopped the hot flashes totally, but I barely have any flashes during the day and have fewer at night (my handy SkyGenius portable fan takes care of those few). I'm getting better sleep--thank God!! This product has the perfect combination of ingredients. I can tell the fibrinolytic enzymes are doing their job. I have several skin cysts that have reduced in size. I highly recommend ladies!!